Jaipur is one of the most famous spots in Rajasthan for IVF treatment. Assuming you’re searching for the ideal family, Mishka IVF is the center to go to. In a warm and inviting climate, you will track down different administrations and the latest innovation.
What can IVF lab work do to improve the success rate?
This webinar was presented by Alpesh Doshi (Consultant Embryologist & Lab director at IVF London). Alpesh spoke about the various options available in embryology labs that can increase success rates for IVF treatments.
Alpesh Doshi spoke about the importance and role of the embryology lab in optimizing success rates during his presentation. Alpesh stressed that it is important to realize that clinical success rates exist. Therefore, your clinicians are important. However, you also want to ensure that the embryology laboratory is generating the best success rates. The success rate of an IVF clinic is determined by the combination of the doctor or clinician and the embryologist.
Optimizing patient outcomes means personalizing patient care or treatment process. Because every patient is unique, it’s important not to treat them as one size fits all. It’s possible to select the best embryo for each patient by carefully watching the embryo’s development. The selection of embryos is patient-centric. Each embryo is carefully examined based on the couple. It is important to monitor embryo development closely to be able to select embryos for transfer.
In Vitro Fertilization (IVF)
Infertility clinics offer IVF as a primary option for couples who are experiencing infertility. There are many stages to IVF treatment. First, IVF treatment involves ovarian stimulation using hormones or medication. This is where multiple follicles are expected to grow in the ovaries. Regular ultrasound scans are performed during ovarian stimulation or follicular stimulation. This is to ensure that the follicles grow as expected. The egg collection procedure is used to retrieve eggs once they have reached a certain size.
It is simple and takes only 30 minutes. The patient is then sedated and a needle is passed through their vaginal wall. Finally, the follicles or all of them are aspirated. The sperm must also be prepared the morning before the egg collection. This is done by the male partner who will collect a sample of sperm.
The laboratory will prepare the sperm for fertilization. The sperm and eggs are then inseminated together using either conventional IVF (if the sperm quality is good) or intracytoplasmic sperm injection (if the sperm parameters are very poor). Regardless of whether you use IVF or ICSI, it is purely based on sperm parameters. Once the eggs have been inseminated and fertilized, the journey involves continuous monitoring and, if necessary, the transfer of one of the embryos back to the uterus. We would also freeze any remaining embryos if they have developed further.
ICSI (Intracytoplasmic Sperm Injection)
In cases of severe male factor fertility, ICSI is used to inseminate eggs. ICSI is recommended if the sperm count is less than 10 million. A semen analysis is the first step in any decision regarding the sperm or the method of insemination. After the semen analysis, the count, motility, and morphology are evaluated. Then, it is decided whether conventional IVF or ICSI will be used for fertilization.
Some men may have a very low count of sperm, perhaps less than 1,000,000. ICSI is therefore the only option. We could not possibly find any sperm in the egg sacs of very few men. This means that they might need to have a more thorough urological evaluation by a consultant physician to determine if there is any blockage in the reproductive tract which is stopping the sperm from flowing out. The urologist might recommend an invasive procedure such as a testicular biopsy if there is any type of blockage. The sperm is extracted from the testicle and taken to the ICSI laboratory.
IMSI (Intracytoplasmic Moologically Selective Sperm Injection).
IMSI stands for Intracytoplasmic Morphologically Selective Sperm Injection. It is recommended in cases of multiple miscarriages or high sperm fragmentation.
It works in the same way as ICSI. However, the sperm can be magnified up to nearly 1000 to 6000x to view the details within the sperm head. This can give an even better picture of the health and condition of the sperm. If embryologists magnify the sperm to this extent, they might be able to identify sperm that are more healthy and have higher implantation potential.
Embryo grading & embryo transfer
Day 0, the egg is already in the body. On day 2, the embryo is in normal fertilization. On day 3, the embryo should have between 2 and 4 or 2 and 5 cell development. On day 3, the embryo should have between 6 and 10 cells. By day 5, five days after egg collection the embryo should reach the blastocyst stage, which is an embryo that has more than 150 cells. It’s at this stage that embryo transfers are most effective. Although embryo transfers can be performed on either day 3 or 5, we recommend pushing embryo transfers to blastocysts to increase the chances of patients becoming pregnant. We know that nature has its channels in terms of which embryos will make it to the blastocyst.
